Apparent lack of conversion of sitosterol into C24-bile acids in humans.
نویسندگان
چکیده
منابع مشابه
C,,-bile acids in humans
The metabolic fate of intravenously administered [4-14C]sitosterol was studied in two healthy subjects. In marked contrast to the results of a previous investigation with [22,233H]sitosterol, no detectable labeled Cz4-bile acid products appeared in bile. The first and rate-limiting step in the conversion of cholesterol into bile acids is catalyzed by the liver microsomal cholesterol 7a-hydroxyl...
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ژورنال
عنوان ژورنال: Journal of Lipid Research
سال: 1990
ISSN: 0022-2275
DOI: 10.1016/s0022-2275(20)42748-8